Spindle cell larynx carcinoma (SpCC) represents around 3% of laryngeal cancers. It is originated by a single cancer stem cell undergoing epithelial to mesenchymal transition. This explains the aggressiveness, the peculiar resistance to conventional therapy and the frequent relapses. We focused on this particular cancer subset characteristics in patients, in early and advanced stages primarily aiming to define and highlight the differences with Laryngeal Squamous Cell Carcinoma (LSCC) focusing on clinical features, treatments, follow-up and survival in a patient's cohort composed by comparable cases from two subgroups.
Sarcomatoid larynx carcinoma differential clinical evolution, on field statistical considerations / Ricciardiello, F.; Bocchetti, M.; Pellini, R.; Palladino, R.; Caraglia, M.; Boscaino, A.; Petruzzi, G.; Romano, F. J.; Chiurazzi, B.; Addeo, R.; Mazzone, S.; Mesolella, M.; Oliva, F.; Iorio, B.. - In: AMERICAN JOURNAL OF OTOLARYNGOLOGY. - ISSN 0196-0709. - (2021), pp. 1-5. [10.1016/j.amjoto.2021.102934]
Sarcomatoid larynx carcinoma differential clinical evolution, on field statistical considerations
Ricciardiello F.;Bocchetti M.;Palladino R.;Petruzzi G.;Romano F. J.;Addeo R.;Mazzone S.;Mesolella M.;Oliva F.;Iorio B.
2021
Abstract
Spindle cell larynx carcinoma (SpCC) represents around 3% of laryngeal cancers. It is originated by a single cancer stem cell undergoing epithelial to mesenchymal transition. This explains the aggressiveness, the peculiar resistance to conventional therapy and the frequent relapses. We focused on this particular cancer subset characteristics in patients, in early and advanced stages primarily aiming to define and highlight the differences with Laryngeal Squamous Cell Carcinoma (LSCC) focusing on clinical features, treatments, follow-up and survival in a patient's cohort composed by comparable cases from two subgroups.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
