Oral cancers have been proven to arise from precursors lesions and to be related to risk behaviour such as alcohol consumption and smoke. However, the present paper focuses on the role of chronic inflammation, related to chronical oral infections and/or altered immune responses occurring during dysimmune and autoimmune diseases, in the oral cancerogenesis. Particularly, oral candidiasis and periodontal diseases introduce a vicious circle of nonhealing and perpetuation of the inflammatory processes, thus leading toward cancer occurrence via local and systemic inflammatory modulators and via genetic and epigenetic factors.

Sex Hormones and Inflammation Role in Oral Cancer Progression: A Molecular and Biological Point of View / Contaldo, M.; Boccellino, M.; Zannini, G.; Romano, A.; Sciarra, A.; Sacco, A.; Settembre, G.; Coppola, M.; Di Carlo, A.; D'Angelo, L.; Inchingolo, F.; Feola, A.; Di Domenico, M.. - In: JOURNAL OF ONCOLOGY. - ISSN 1687-8469. - 2020:(2020), pp. 1-14. [10.1155/2020/9587971]

Sex Hormones and Inflammation Role in Oral Cancer Progression: A Molecular and Biological Point of View

Di Carlo A.;Feola A.
Penultimo
Conceptualization
;
Di Domenico M.
2020

Abstract

Oral cancers have been proven to arise from precursors lesions and to be related to risk behaviour such as alcohol consumption and smoke. However, the present paper focuses on the role of chronic inflammation, related to chronical oral infections and/or altered immune responses occurring during dysimmune and autoimmune diseases, in the oral cancerogenesis. Particularly, oral candidiasis and periodontal diseases introduce a vicious circle of nonhealing and perpetuation of the inflammatory processes, thus leading toward cancer occurrence via local and systemic inflammatory modulators and via genetic and epigenetic factors.
2020
Sex Hormones and Inflammation Role in Oral Cancer Progression: A Molecular and Biological Point of View / Contaldo, M.; Boccellino, M.; Zannini, G.; Romano, A.; Sciarra, A.; Sacco, A.; Settembre, G.; Coppola, M.; Di Carlo, A.; D'Angelo, L.; Inchingolo, F.; Feola, A.; Di Domenico, M.. - In: JOURNAL OF ONCOLOGY. - ISSN 1687-8469. - 2020:(2020), pp. 1-14. [10.1155/2020/9587971]
File in questo prodotto:
File Dimensione Formato  
contaldo et al. 2020.pdf

accesso aperto

Tipologia: Documento in Post-print
Licenza: Dominio pubblico
Dimensione 1.52 MB
Formato Adobe PDF
1.52 MB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/816610
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 19
  • ???jsp.display-item.citation.isi??? 20
social impact