Arginine (L-arginine), is an amino acid involved in a number of biological processes, including the biosynthesis of proteins, host immune response, urea cycle, and nitric oxide production. In this systematic review, we focus on the functional role of arginine in the regulation of endothelial function and vascular tone. Both clinical and preclinical studies are examined, analyzing the effects of arginine supplementation in hypertension, ischemic heart disease, aging, peripheral artery disease, and diabetes mellitus.

Arginine and Endothelial Function / Gambardella, Jessica; Khondkar, Wafiq; Morelli, Marco Bruno; Wang, Xujun; Santulli, Gaetano; Trimarco, Valentina. - In: BIOMEDICINES. - ISSN 2227-9059. - 8:8(2020), p. 277. [10.3390/biomedicines8080277]

Arginine and Endothelial Function

Gambardella, Jessica
Primo
Writing – Original Draft Preparation
;
Santulli, Gaetano
Supervision
;
Trimarco, Valentina
Validation
2020

Abstract

Arginine (L-arginine), is an amino acid involved in a number of biological processes, including the biosynthesis of proteins, host immune response, urea cycle, and nitric oxide production. In this systematic review, we focus on the functional role of arginine in the regulation of endothelial function and vascular tone. Both clinical and preclinical studies are examined, analyzing the effects of arginine supplementation in hypertension, ischemic heart disease, aging, peripheral artery disease, and diabetes mellitus.
2020
Arginine and Endothelial Function / Gambardella, Jessica; Khondkar, Wafiq; Morelli, Marco Bruno; Wang, Xujun; Santulli, Gaetano; Trimarco, Valentina. - In: BIOMEDICINES. - ISSN 2227-9059. - 8:8(2020), p. 277. [10.3390/biomedicines8080277]
File in questo prodotto:
File Dimensione Formato  
biomedicines-08-00277-v2(2).pdf

non disponibili

Tipologia: Documento in Post-print
Licenza: Creative commons
Dimensione 1.02 MB
Formato Adobe PDF
1.02 MB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/815660
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 150
  • ???jsp.display-item.citation.isi??? 130
social impact