Cell-penetrating peptides (CPPs) are short peptides able to cross the cellular membranes without any interaction with specific receptors. Thanks to their ability to transport various cargo inside the cells are emerged as powerful therapeutic agents alternative to small molecules. In recent years, numerous preclinical studies provided promising results for the treatment of various human diseases. Several CPP-conjugated compounds are under clinical trials.
Cell-penetrating peptides: two faces of the same coin / Pierantoni, Giovanna Maria; Paladino, Simona. - In: BIOCHEMICAL JOURNAL. - ISSN 0264-6021. - 477:8(2020), pp. 1363-1366. [10.1042/BCJ20200006]
Cell-penetrating peptides: two faces of the same coin
Pierantoni, Giovanna Maria;Paladino, Simona
2020
Abstract
Cell-penetrating peptides (CPPs) are short peptides able to cross the cellular membranes without any interaction with specific receptors. Thanks to their ability to transport various cargo inside the cells are emerged as powerful therapeutic agents alternative to small molecules. In recent years, numerous preclinical studies provided promising results for the treatment of various human diseases. Several CPP-conjugated compounds are under clinical trials.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
