This review article highlights some important points in the evolving area of predictive biomarkers determination in non-small-cell lung cancer toward standardization of testing practices, including EGFR mutations, ALK and ROS1 rearrangements and immunohistochemical expression of PD-L1. Considerations for selecting appropriate populations for molecular testing, and emergence of other targetable molecular alterations are also discussed.
Predictive markers in lung cancer: a few hints for the practicing pathologist / Barbareschi, M; Barberis, M; Buttitta, F; Doglioni, Francesco; Fiorentino, M; Fontanini, Gabriella; Franco, R; Marchetti, A; Rossi, G; Troncone, G. - In: PATHOLOGICA. - ISSN 1591-951X. - 110:1(2018), p. 29-38.
Predictive markers in lung cancer: a few hints for the practicing pathologist
DOGLIONI, FRANCESCOMembro del Collaboration Group
;FONTANINI, GABRIELLAMembro del Collaboration Group
;Troncone, GMembro del Collaboration Group
2018
Abstract
This review article highlights some important points in the evolving area of predictive biomarkers determination in non-small-cell lung cancer toward standardization of testing practices, including EGFR mutations, ALK and ROS1 rearrangements and immunohistochemical expression of PD-L1. Considerations for selecting appropriate populations for molecular testing, and emergence of other targetable molecular alterations are also discussed.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
