The prevalence of mental diseases, especially neurodegenerative disorders, is ever-increasing, while treatment options for such disorders are limited and insufficient. In this scarcity of available medication, it is a feasible strategy to search for potential drugs among natural compounds, such as those found in plants. One such plant source is the root of Chinese sage, Salvia miltiorrhiza Bunge (Labiatae), which contains several compounds reported to possess neuroprotective activities. The most important of these compounds are tanshinones, which have been reported to possess ameliorative activity against a myriad of mental diseases such as Alzheimer's disease, cerebral ischemia/reperfusion injury, and glioma, along with promoting neuronal differentiation and manifesting antinociceptive and anticonvulsant outcomes. This review offers a critical evaluation of the utility of tanshinones to treat mental illnesses, and sheds light on the underlying mechanisms through which these naturally occurring compounds confer neuroprotection.

Tanshinones and mental diseases: from chemistry to medicine / Javed, Sana; Tariq, Ameema; Ahmed, Touqeer; Budzyńska, Barbara; Tejada, Silvia; Daglia, Maria; Nabavi Seyed, Fazel; Sobarzo-Sánchez, Eduardo; Nabavi Seyed, Mohammad. - In: REVIEWS IN THE NEUROSCIENCES. - ISSN 0334-1763. - 27:8(2016), pp. 777-779. [10.1515/revneuro-2016-0012]

Tanshinones and mental diseases: from chemistry to medicine

Daglia Maria;
2016

Abstract

The prevalence of mental diseases, especially neurodegenerative disorders, is ever-increasing, while treatment options for such disorders are limited and insufficient. In this scarcity of available medication, it is a feasible strategy to search for potential drugs among natural compounds, such as those found in plants. One such plant source is the root of Chinese sage, Salvia miltiorrhiza Bunge (Labiatae), which contains several compounds reported to possess neuroprotective activities. The most important of these compounds are tanshinones, which have been reported to possess ameliorative activity against a myriad of mental diseases such as Alzheimer's disease, cerebral ischemia/reperfusion injury, and glioma, along with promoting neuronal differentiation and manifesting antinociceptive and anticonvulsant outcomes. This review offers a critical evaluation of the utility of tanshinones to treat mental illnesses, and sheds light on the underlying mechanisms through which these naturally occurring compounds confer neuroprotection.
2016
Tanshinones and mental diseases: from chemistry to medicine / Javed, Sana; Tariq, Ameema; Ahmed, Touqeer; Budzyńska, Barbara; Tejada, Silvia; Daglia, Maria; Nabavi Seyed, Fazel; Sobarzo-Sánchez, Eduardo; Nabavi Seyed, Mohammad. - In: REVIEWS IN THE NEUROSCIENCES. - ISSN 0334-1763. - 27:8(2016), pp. 777-779. [10.1515/revneuro-2016-0012]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/766929
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