Lipopolysaccharides (LPSs) are the main components of the external leaflet of the outer membrane of Gram-negative bacteria. Microorganisms that colonize permanently or transiently cold habitats have evolved an array of structural adaptations, some of which involve components of bacterial membranes. These adaptations assure the perfect functionality of the membrane even at freezing or sub-freezing growth temperatures. This review summarizes the state-of-the-art information concerning the structural features of the LPSs produced by cold-adapted bacteria. The LPS structure has recently been elucidated from species mainly belonging to Gammaproteobacteria and Flavobacteriaceae. Although the reported structural heterogeneity may arise from the phylogenetic diversity of the analyzed source strains, some generalized trends can be deduced. For instance, it is clear that only a small portion of LPSs displays the O-chain. In addition, the biological activity of the lipid A portion from several cold-adapted strains is reported.

The outer membrane glycolipids of bacteria from cold environments: Isolation, characterization, and biological activity / Casillo, A.; Parrilli, E.; Tutino, M. L.; Corsaro, M. M.. - In: FEMS MICROBIOLOGY ECOLOGY. - ISSN 0168-6496. - 95:7(2019), pp. 1-14. [10.1093/femsec/fiz094]

The outer membrane glycolipids of bacteria from cold environments: Isolation, characterization, and biological activity

Casillo A.;Parrilli E.;Tutino M. L.;Corsaro M. M.
2019

Abstract

Lipopolysaccharides (LPSs) are the main components of the external leaflet of the outer membrane of Gram-negative bacteria. Microorganisms that colonize permanently or transiently cold habitats have evolved an array of structural adaptations, some of which involve components of bacterial membranes. These adaptations assure the perfect functionality of the membrane even at freezing or sub-freezing growth temperatures. This review summarizes the state-of-the-art information concerning the structural features of the LPSs produced by cold-adapted bacteria. The LPS structure has recently been elucidated from species mainly belonging to Gammaproteobacteria and Flavobacteriaceae. Although the reported structural heterogeneity may arise from the phylogenetic diversity of the analyzed source strains, some generalized trends can be deduced. For instance, it is clear that only a small portion of LPSs displays the O-chain. In addition, the biological activity of the lipid A portion from several cold-adapted strains is reported.
2019
The outer membrane glycolipids of bacteria from cold environments: Isolation, characterization, and biological activity / Casillo, A.; Parrilli, E.; Tutino, M. L.; Corsaro, M. M.. - In: FEMS MICROBIOLOGY ECOLOGY. - ISSN 0168-6496. - 95:7(2019), pp. 1-14. [10.1093/femsec/fiz094]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/756967
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