Ortho- and meta-nitrobenzaldehydes are two important intermediates in the chemical industry. They are the main products of benzaldehyde nitration by mixed acid, which is a hazardous chemical process since reaction rates are very sensitive to variations of the operating conditions. In the present investigation, a previously developed kinetic model under homogeneous conditions is validated and extended for heterogeneous liquid-liquid systems. A comparison between performances of a lab-scale batch reactor and a commercial microreactor is also presented. The results show that microreactors with embedded static mixer can outperform scaled-up batch reactors, achieving the theoretical limit of conversion/yield attainable under kinetic control.

Heterogeneous benzaldehyde nitration in batch and continuous flow microreactor / Russo, Danilo; Tomaiuolo, Giovanna; Andreozzi, Roberto; Guido, Stefano; Lapkin, Alexei A.; Di Somma, Ilaria; Tomaiuolo, Giovanna. - In: CHEMICAL ENGINEERING JOURNAL. - ISSN 1385-8947. - 377:(2019), p. 120346. [10.1016/j.cej.2018.11.044]

Heterogeneous benzaldehyde nitration in batch and continuous flow microreactor

Russo, Danilo;Andreozzi, Roberto;Guido, Stefano;Di Somma, Ilaria;TOMAIUOLO, GIOVANNA
2019

Abstract

Ortho- and meta-nitrobenzaldehydes are two important intermediates in the chemical industry. They are the main products of benzaldehyde nitration by mixed acid, which is a hazardous chemical process since reaction rates are very sensitive to variations of the operating conditions. In the present investigation, a previously developed kinetic model under homogeneous conditions is validated and extended for heterogeneous liquid-liquid systems. A comparison between performances of a lab-scale batch reactor and a commercial microreactor is also presented. The results show that microreactors with embedded static mixer can outperform scaled-up batch reactors, achieving the theoretical limit of conversion/yield attainable under kinetic control.
2019
Heterogeneous benzaldehyde nitration in batch and continuous flow microreactor / Russo, Danilo; Tomaiuolo, Giovanna; Andreozzi, Roberto; Guido, Stefano; Lapkin, Alexei A.; Di Somma, Ilaria; Tomaiuolo, Giovanna. - In: CHEMICAL ENGINEERING JOURNAL. - ISSN 1385-8947. - 377:(2019), p. 120346. [10.1016/j.cej.2018.11.044]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/749526
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