An intriguing piece of evidence for the inflammatory story of type 2 diabetes has come to the light. A recent study by Okin and colleagues adds new clues to the interplay between cholesterol metabolism and immunity and how it impacts glucose homeostasis in inflammatory conditions. But some questions are a still unsolved conundrum. Here we suggest to better dissect the regulatory mechanism of Mevalonate pathway and to underpin a new causative link between immunometabolic dysregulation and diabetes.

The complex interplay among hepatocytes and immune cells at the crossroad between inflammation and cholesterol metabolism in hyperglycemia / Bifulco, Maurizio; Pisanti, Simona; Ciaglia, Elena. - In: ENDOCRINE. - ISSN 1355-008X. - 58:1(2017), pp. 21-23. [10.1007/s12020-017-1254-0]

The complex interplay among hepatocytes and immune cells at the crossroad between inflammation and cholesterol metabolism in hyperglycemia

Bifulco Maurizio;
2017

Abstract

An intriguing piece of evidence for the inflammatory story of type 2 diabetes has come to the light. A recent study by Okin and colleagues adds new clues to the interplay between cholesterol metabolism and immunity and how it impacts glucose homeostasis in inflammatory conditions. But some questions are a still unsolved conundrum. Here we suggest to better dissect the regulatory mechanism of Mevalonate pathway and to underpin a new causative link between immunometabolic dysregulation and diabetes.
2017
The complex interplay among hepatocytes and immune cells at the crossroad between inflammation and cholesterol metabolism in hyperglycemia / Bifulco, Maurizio; Pisanti, Simona; Ciaglia, Elena. - In: ENDOCRINE. - ISSN 1355-008X. - 58:1(2017), pp. 21-23. [10.1007/s12020-017-1254-0]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/747025
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