Vitamin D is a pro-hormone belonging to the category of the fat-soluble group of vitamins; it is obtained more from solar exposure and in smaller quantities through feeding. Although vitamin D has traditionally been shown to be involved in calcium homeostasis and bone health, recent studies have found a positive association between vitamin D and sleep. In particular, clinical studies in humans indicate that low levels of vitamin D are correlated with poor quality and short sleep duration. The mechanism by which this association is explained is still unclear. However, vitamin D receptors have been found in the brain regions involved in sleep regulation, and vitamin D appears to be involved in regulating the sleep-wake cycle. The current review summarizes the available evidence regarding the association between vitamin D and sleep, focusing on both clinical and preclinical studies.
The lullaby of the sun: the role of vitamin D in sleep disturbance / Muscogiuri, G; Barrea, L; Scannapieco, M; Di Somma, C; Scacchi, M; Aimaretti, G; Savastano, S; Colao, A; Marzullo, P.. - In: SLEEP MEDICINE. - ISSN 1389-9457. - 54:(2019), pp. 262-265. [10.1016/j.sleep.2018.10.033]
The lullaby of the sun: the role of vitamin D in sleep disturbance.
Muscogiuri G
;Barrea L;Di Somma C;Savastano S;Colao A;
2019
Abstract
Vitamin D is a pro-hormone belonging to the category of the fat-soluble group of vitamins; it is obtained more from solar exposure and in smaller quantities through feeding. Although vitamin D has traditionally been shown to be involved in calcium homeostasis and bone health, recent studies have found a positive association between vitamin D and sleep. In particular, clinical studies in humans indicate that low levels of vitamin D are correlated with poor quality and short sleep duration. The mechanism by which this association is explained is still unclear. However, vitamin D receptors have been found in the brain regions involved in sleep regulation, and vitamin D appears to be involved in regulating the sleep-wake cycle. The current review summarizes the available evidence regarding the association between vitamin D and sleep, focusing on both clinical and preclinical studies.File | Dimensione | Formato | |
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