The analysis of cardiac damage biomarkers is crucial in the diagnosis and prognosis of acute myocardial infarction. The present work proposes a dynamical model for the analysis of the release in the blood of cardiac troponin T (cTnT). The model, tested against patients data, proves to be an effective tool to extrapolate information of interest to the clinician, like peaks and peak-times of the release curve. Furthermore, the model has been proven efficient to quantitatively differentiate patients with effective and non-effective thrombolysis response, which is a key information to guide revascularization.
A model of cardiac troponin T release in patient with acute myocardial infarction / Procopio, A., De Rosa, S., Covello, C., Merola, A., Sabatino, J., De Luca, A., Indolfi, C., Amato, F., Cosentino, C.. - 2018-:(2017), pp. 435-440. (56th IEEE Annual Conference on Decision and Control, CDC 2017 Melbourne Convention and Exhibition Centre (MCEC), aus 2017) [10.1109/CDC.2017.8263703].
A model of cardiac troponin T release in patient with acute myocardial infarction
Amato, Francesco;
2017
Abstract
The analysis of cardiac damage biomarkers is crucial in the diagnosis and prognosis of acute myocardial infarction. The present work proposes a dynamical model for the analysis of the release in the blood of cardiac troponin T (cTnT). The model, tested against patients data, proves to be an effective tool to extrapolate information of interest to the clinician, like peaks and peak-times of the release curve. Furthermore, the model has been proven efficient to quantitatively differentiate patients with effective and non-effective thrombolysis response, which is a key information to guide revascularization.| File | Dimensione | Formato | |
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