Schizophrenia is a complex illness in which genetic, environmental, and epigenetic components have been implicated. However, recently, psychiatric disorders appear to be related to a chronic inflammatory state, at the level of specific cerebral areas which have been found as well impaired and responsible of the schizophrenia symptomatology. Hence, a role of inflammatory mediators and cytokines has been as well supposed. Accordingly, it has been recently investigated the role of an acute inflammatory phase protein, the C-reactive protein (CRP).
Protein-C reactive as biomarker predictor of schizophrenia phases of illness? A systematic review / Orsolini, Laura; Sarchione, Fabiola; Vellante, Federica; Fornaro, Michele; Matarazzo, Ilaria; Martinotti, Giovanni; Valchera, Alessandro; Di Nicola, Marco; Carano, Alessandro; Di Giannantonio, Massimo; Perna, Giampaolo; Olivieri, Luigi; De Berardis, Domenico. - In: CURRENT NEUROPHARMACOLOGY. - ISSN 1570-159X. - (2018). [10.2174/1570159X16666180119144538]
Protein-C reactive as biomarker predictor of schizophrenia phases of illness? A systematic review
Fornaro, Michele;
2018
Abstract
Schizophrenia is a complex illness in which genetic, environmental, and epigenetic components have been implicated. However, recently, psychiatric disorders appear to be related to a chronic inflammatory state, at the level of specific cerebral areas which have been found as well impaired and responsible of the schizophrenia symptomatology. Hence, a role of inflammatory mediators and cytokines has been as well supposed. Accordingly, it has been recently investigated the role of an acute inflammatory phase protein, the C-reactive protein (CRP).File | Dimensione | Formato | |
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