Several randomised controlled trials (RCTs) on the use of probiotics to reduce morbidity and mortality in preterm infants have provided inconsistent results. Whilst meta-analyses that group all of the used strains together, suggest efficacy, it is not possible to determine the most effective strain which is more relevant to the clinician. We therefore used a network meta-analysis (NMA) approach in order to identify strains with greatest efficacy.
Probiotics for Preterm Infants: a strain specific systematic review and network meta-analysis / Berni Canani, R; Domellöf, M; Guarino, A; Indrio, F; Kolaček, S; Mihatsch, Wa; Orel, R; Vandenplas, Y; Weizman, Z.. - In: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. - ISSN 0277-2116. - (2018), pp. 1-103. [10.1097/MPG.0000000000001897]
Probiotics for Preterm Infants: a strain specific systematic review and network meta-analysis
Berni Canani R;Guarino A;
2018
Abstract
Several randomised controlled trials (RCTs) on the use of probiotics to reduce morbidity and mortality in preterm infants have provided inconsistent results. Whilst meta-analyses that group all of the used strains together, suggest efficacy, it is not possible to determine the most effective strain which is more relevant to the clinician. We therefore used a network meta-analysis (NMA) approach in order to identify strains with greatest efficacy.| File | Dimensione | Formato | |
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Probiotics for preterm infants a strain specific systematic review and network meta-analysis.pdf
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