ObjectiveaaWe investigate the presence and the quality of pain in patients with dystrophic EB (DEB), and correlate it with the level of anxiety and depression. MethodsaaWe collected data from 27 DEB patients and 26 healthy individuals. DEB patients and controls completed 1 scale for the quality of pain, and 1 scale for anxiety and depression. Pain was assessed with the short form of the McGill Pain Questionnaire (MPQ-SF), whereas anxiety and depression were assessed with the Hamilton rating scale for anxiety (HAM-A) and depression (HAM-D). ResultsaaDEB patients and healthy control individuals were homogeneous for age and gender (p>0.05). A statistically significant difference in the two groups was seen for S-PRI (p<0.001), A-PRI (p=0.029), T-PRI (p<0.001), VAS (p=0.012) and PPI (p=0.001), but not for anxiety (p=0.169) and depression (p=0.530). The characteristics of pain that showed a significant difference between DEB patients and healthy controls were shooting, splitting, tender and throbbing (p<0.05). In DEB patients pain was not correlated with anxiety or depression (p>0.05), whereas a slight correlation between pain and anxiety was found in healthy controls (p<0.05). No difference was found between quality of pain and anxiety-depression in DEB patients (p>0.05), but was between the DEB dominant and the recessive form of DEB (p=0.025). ConclusionaaThe perception of pain in DEB patients appears greater than in healthy individuals, with splitting and tender characteristics being the most significant ones, but was not associated with anxious and/or depressive symptoms.

Pain in Patients with Dystrophic Epidermolysis Bullosa: Association with Anxiety and Depression / Fortuna, Giulio; Aria, Massimo; Rodrigo, Cepeda Valdes; Maria, Guadalupe Moreno Trevino; Julio, Cesar Salas Alan. - In: PSYCHIATRY INVESTIGATION. - ISSN 1738-3684. - 15:(2017). [10.4306/pi.2017.14.6.746]

Pain in Patients with Dystrophic Epidermolysis Bullosa: Association with Anxiety and Depression

FORTUNA, GIULIO
;
Aria, Massimo;
2017

Abstract

ObjectiveaaWe investigate the presence and the quality of pain in patients with dystrophic EB (DEB), and correlate it with the level of anxiety and depression. MethodsaaWe collected data from 27 DEB patients and 26 healthy individuals. DEB patients and controls completed 1 scale for the quality of pain, and 1 scale for anxiety and depression. Pain was assessed with the short form of the McGill Pain Questionnaire (MPQ-SF), whereas anxiety and depression were assessed with the Hamilton rating scale for anxiety (HAM-A) and depression (HAM-D). ResultsaaDEB patients and healthy control individuals were homogeneous for age and gender (p>0.05). A statistically significant difference in the two groups was seen for S-PRI (p<0.001), A-PRI (p=0.029), T-PRI (p<0.001), VAS (p=0.012) and PPI (p=0.001), but not for anxiety (p=0.169) and depression (p=0.530). The characteristics of pain that showed a significant difference between DEB patients and healthy controls were shooting, splitting, tender and throbbing (p<0.05). In DEB patients pain was not correlated with anxiety or depression (p>0.05), whereas a slight correlation between pain and anxiety was found in healthy controls (p<0.05). No difference was found between quality of pain and anxiety-depression in DEB patients (p>0.05), but was between the DEB dominant and the recessive form of DEB (p=0.025). ConclusionaaThe perception of pain in DEB patients appears greater than in healthy individuals, with splitting and tender characteristics being the most significant ones, but was not associated with anxious and/or depressive symptoms.
2017
Pain in Patients with Dystrophic Epidermolysis Bullosa: Association with Anxiety and Depression / Fortuna, Giulio; Aria, Massimo; Rodrigo, Cepeda Valdes; Maria, Guadalupe Moreno Trevino; Julio, Cesar Salas Alan. - In: PSYCHIATRY INVESTIGATION. - ISSN 1738-3684. - 15:(2017). [10.4306/pi.2017.14.6.746]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/683343
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