Aim of our study was to assess the ovulation rate, with mid-luteal progesterone level and ultrasound follicles monitoring, in PCOS CC-resistant patients undergone transvaginal hydrolaparoscopy ovarian drilling. A prospective observational study was carried out in 123 PCOS, infertile, CC-resistant patients who undergone THL ovarian drilling. Each woman was evaluated by hormonal measurement, and ultrasound evaluation during 6 months follow-up. Progesterone serum levels were assessed on days 20-24 of the cycle after surgical treatment. Pg levels >3 ng/mL were considered as ovulation. Ovulation frequency and the highest mean follicular diameters during the monitoring were recorded. 117 patients complete the study, since six patients were lost to follow-up. Mean follicular diameter during ovulation monitoring was 16.37 mm. Ovulation rate at the follow up was 64.1% one month after treatment, 79.5% after three months and 82.9% after six months. 28 patients conceived during follow-up period. Pregnancy rate was 70.1%. Our study has shown that THL ovarian drilling improves ovulation and pregnancy rate in women with CC-resistant PCOS. We believe that this approach should be offered as second-line therapy at all PCOS CC-resistant women who fail the medical methods of ovulation induction.

Operative transvaginal hydrolaparoscopy improve ovulation rate after clomiphene failure in polycystic ovary syndrome / Giampaolino, Pierluigi; DE ROSA, Nicoletta; DELLA CORTE, Luigi; Morra, Ilaria; Mercorio, Antonio; Nappi, Carmine; Bifulco, Giuseppe. - In: GYNECOLOGICAL ENDOCRINOLOGY. - ISSN 0951-3590. - 34:(2018), pp. 32-35. [10.1080/09513590.2017.1323204]

Operative transvaginal hydrolaparoscopy improve ovulation rate after clomiphene failure in polycystic ovary syndrome

GIAMPAOLINO, PIERLUIGI;DE ROSA, NICOLETTA;DELLA CORTE, LUIGI;MORRA, ILARIA;NAPPI, CARMINE;BIFULCO, GIUSEPPE
2018

Abstract

Aim of our study was to assess the ovulation rate, with mid-luteal progesterone level and ultrasound follicles monitoring, in PCOS CC-resistant patients undergone transvaginal hydrolaparoscopy ovarian drilling. A prospective observational study was carried out in 123 PCOS, infertile, CC-resistant patients who undergone THL ovarian drilling. Each woman was evaluated by hormonal measurement, and ultrasound evaluation during 6 months follow-up. Progesterone serum levels were assessed on days 20-24 of the cycle after surgical treatment. Pg levels >3 ng/mL were considered as ovulation. Ovulation frequency and the highest mean follicular diameters during the monitoring were recorded. 117 patients complete the study, since six patients were lost to follow-up. Mean follicular diameter during ovulation monitoring was 16.37 mm. Ovulation rate at the follow up was 64.1% one month after treatment, 79.5% after three months and 82.9% after six months. 28 patients conceived during follow-up period. Pregnancy rate was 70.1%. Our study has shown that THL ovarian drilling improves ovulation and pregnancy rate in women with CC-resistant PCOS. We believe that this approach should be offered as second-line therapy at all PCOS CC-resistant women who fail the medical methods of ovulation induction.
2018
Operative transvaginal hydrolaparoscopy improve ovulation rate after clomiphene failure in polycystic ovary syndrome / Giampaolino, Pierluigi; DE ROSA, Nicoletta; DELLA CORTE, Luigi; Morra, Ilaria; Mercorio, Antonio; Nappi, Carmine; Bifulco, Giuseppe. - In: GYNECOLOGICAL ENDOCRINOLOGY. - ISSN 0951-3590. - 34:(2018), pp. 32-35. [10.1080/09513590.2017.1323204]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/682750
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