A significant proportion (∼15%) of colorectal cancer (CRC), either sporadic or arising in the setting of the hereditary non-polyposis colorectal carcinoma syndrome, features microsatellite instability (MSI). Five MSI loci, either mononucleotide or dinucleotide repeats (Bat25, Bat26, D2S123, D5S346 and D17S250), are included in the Bethesda panel and capillary electrophoresis represents the usual gold standard technique.

Microsatellite instability evaluation by automated microfluidic electrophoresis: an update / Pepe, Francesco; Smeraglio, Riccardo; Vacirca, Davide; Malapelle, Umberto; Barberis, Massimo; Troncone, Giancarlo. - In: JOURNAL OF CLINICAL PATHOLOGY. - ISSN 0021-9746. - 70:1(2017), pp. 90-91-91. [10.1136/jclinpath-2016-204200]

Microsatellite instability evaluation by automated microfluidic electrophoresis: an update

PEPE, FRANCESCO;MALAPELLE, UMBERTO;TRONCONE, GIANCARLO
2017

Abstract

A significant proportion (∼15%) of colorectal cancer (CRC), either sporadic or arising in the setting of the hereditary non-polyposis colorectal carcinoma syndrome, features microsatellite instability (MSI). Five MSI loci, either mononucleotide or dinucleotide repeats (Bat25, Bat26, D2S123, D5S346 and D17S250), are included in the Bethesda panel and capillary electrophoresis represents the usual gold standard technique.
2017
Microsatellite instability evaluation by automated microfluidic electrophoresis: an update / Pepe, Francesco; Smeraglio, Riccardo; Vacirca, Davide; Malapelle, Umberto; Barberis, Massimo; Troncone, Giancarlo. - In: JOURNAL OF CLINICAL PATHOLOGY. - ISSN 0021-9746. - 70:1(2017), pp. 90-91-91. [10.1136/jclinpath-2016-204200]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/682287
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