The 1,2-decanediol (S-Mal) is an organic compound belonging to the 1,2- alkanediol family, with two hydroxyl groups located on the first and second carbon of the alkane chain, probably responsible for the enhanced anti-bacterial efficacy. The willow bark total extract (W-Mal) has been used since thousands of years as an herbal remedy for its antipyretic, analgesic, anti-inflammatory and anti-microbial activities. S-Mal is used in cosmetic preparations, whether W- Mal can be topically or systemically administered. Aim of our study was to evaluate in vitro the anti-inflammatory and antioxidant properties of S-Mal and W-Mal, singularly or in combination, in LPS-stimulated keratinocytes.

The anti-inflammatory and antioxidant properties of 1,2-decanediol and willow bark extract in lipopolysaccharide-stimulated keratinocytes / DI CAPRIO, Roberta; Monfrecola, Giuseppe; Balato, Anna; Balato, Nicola; Gasparri, Franco; Micillo, Raffaella; Lembo, Serena. - In: GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA. - ISSN 1827-1820. - (2019). [10.23736/S0392-0488.17.05592-4]

The anti-inflammatory and antioxidant properties of 1,2-decanediol and willow bark extract in lipopolysaccharide-stimulated keratinocytes

DI CAPRIO, ROBERTA;MONFRECOLA, GIUSEPPE;BALATO, ANNA;BALATO, NICOLA;Micillo, Raffaella;LEMBO, SERENA
2019

Abstract

The 1,2-decanediol (S-Mal) is an organic compound belonging to the 1,2- alkanediol family, with two hydroxyl groups located on the first and second carbon of the alkane chain, probably responsible for the enhanced anti-bacterial efficacy. The willow bark total extract (W-Mal) has been used since thousands of years as an herbal remedy for its antipyretic, analgesic, anti-inflammatory and anti-microbial activities. S-Mal is used in cosmetic preparations, whether W- Mal can be topically or systemically administered. Aim of our study was to evaluate in vitro the anti-inflammatory and antioxidant properties of S-Mal and W-Mal, singularly or in combination, in LPS-stimulated keratinocytes.
2019
The anti-inflammatory and antioxidant properties of 1,2-decanediol and willow bark extract in lipopolysaccharide-stimulated keratinocytes / DI CAPRIO, Roberta; Monfrecola, Giuseppe; Balato, Anna; Balato, Nicola; Gasparri, Franco; Micillo, Raffaella; Lembo, Serena. - In: GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA. - ISSN 1827-1820. - (2019). [10.23736/S0392-0488.17.05592-4]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/681212
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