Rheumatoid Arthritis (RA) is an autoimmune inflammatory disease that leads to local and systemic arthritis and bone loss. Exploring genetic markers of candidate genes in osteoporosis and inflammatory cytokine genes could be a useful tool for the early identification of bone loss and fracture risk in RA patients. The target of this study is the evaluation and correlation between of Single Nucleotide Polymorphisms (SNPs) of Vitamin D Receptor (VDR) and possible effects on bone loss in RA.
Vitamin D receptor polymorphisms as tool for early screening of severe bone loss in women patients with rheumatoid arthritis / DI SPIGNA, Gaetano; DEL PUENTE, Antonio; Covelli, Bianca; Abete, E; Varriale, E; Salzano, S; Postiglione, Loredana. - In: EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES. - ISSN 2284-0729. - 20:22(2016), pp. 4664-4669.
Vitamin D receptor polymorphisms as tool for early screening of severe bone loss in women patients with rheumatoid arthritis
DI SPIGNA, GAETANO;DEL PUENTE, ANTONIO;COVELLI, BIANCA;POSTIGLIONE, LOREDANA
2016
Abstract
Rheumatoid Arthritis (RA) is an autoimmune inflammatory disease that leads to local and systemic arthritis and bone loss. Exploring genetic markers of candidate genes in osteoporosis and inflammatory cytokine genes could be a useful tool for the early identification of bone loss and fracture risk in RA patients. The target of this study is the evaluation and correlation between of Single Nucleotide Polymorphisms (SNPs) of Vitamin D Receptor (VDR) and possible effects on bone loss in RA.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
