There are several reviews on NO and hydrogen sulfide (H2 S) and their role in vascular diseases in the current relevant literature. The aim of this review is to discuss, within the limits of present knowledge, the interconnection between these two gasotransmitters in vascular function. In particular, the review focuses on the role played by the balance between the NO and H2 S pathways in either physiological or pathological conditions. The distinction between physiology and pathology has been made in order to dissect the molecular basis of this crosstalk, highlighting how and if this balance varies, depending upon the vascular status. Perspectives and possible novel therapeutic approaches are also discussed.

Nitric oxide and hydrogen sulfide: the gasotransmitter paradigm of the vascular system / Cirino, Giuseppe; Vellecco, Valentina; Bucci, Mariarosaria. - In: BRITISH JOURNAL OF PHARMACOLOGY. - ISSN 1476-5381. - 174:22(2017), pp. 4021-4031. [10.1111/bph.13815.]

Nitric oxide and hydrogen sulfide: the gasotransmitter paradigm of the vascular system.

CIRINO, GIUSEPPE
Primo
;
VELLECCO, VALENTINA;BUCCI, MARIAROSARIA
Ultimo
2017

Abstract

There are several reviews on NO and hydrogen sulfide (H2 S) and their role in vascular diseases in the current relevant literature. The aim of this review is to discuss, within the limits of present knowledge, the interconnection between these two gasotransmitters in vascular function. In particular, the review focuses on the role played by the balance between the NO and H2 S pathways in either physiological or pathological conditions. The distinction between physiology and pathology has been made in order to dissect the molecular basis of this crosstalk, highlighting how and if this balance varies, depending upon the vascular status. Perspectives and possible novel therapeutic approaches are also discussed.
2017
Nitric oxide and hydrogen sulfide: the gasotransmitter paradigm of the vascular system / Cirino, Giuseppe; Vellecco, Valentina; Bucci, Mariarosaria. - In: BRITISH JOURNAL OF PHARMACOLOGY. - ISSN 1476-5381. - 174:22(2017), pp. 4021-4031. [10.1111/bph.13815.]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/678189
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