Copper and zinc are essential micronutrients and cofactors of many enzymatic reactions that may be involved in liver-cancer development. We aimed to assess pre-diagnostic circulating levels of copper, zinc and their ratio (Cu/Zn) in relation to hepatocellular carcinoma (HCC), intrahepatic bile duct (IHBD) and gall bladder and biliary tract (GBTC) cancers.

Circulating copper and zinc levels and risk of hepatobiliary cancers in Europeans / Stepien, M., Hughes, D.J., Hybsier, S., Bamia, C., Tjønneland, A., Overvad, K., Affret, A., His, M., Boutron Ruault, M.C., Katzke, V., Kühn, T., Aleksandrova, K., Trichopoulou, A., Lagiou, P., Orfanos, P., Palli, D., Sieri, S., Tumino, R., Ricceri, F., Panico, S., et al.. - In: BRITISH JOURNAL OF CANCER. - ISSN 1532-1827. - 116:5(2017), p. 688-696. [10.1038/bjc.2017.1]

Circulating copper and zinc levels and risk of hepatobiliary cancers in Europeans

PANICO, SALVATORE;
2017

Abstract

Copper and zinc are essential micronutrients and cofactors of many enzymatic reactions that may be involved in liver-cancer development. We aimed to assess pre-diagnostic circulating levels of copper, zinc and their ratio (Cu/Zn) in relation to hepatocellular carcinoma (HCC), intrahepatic bile duct (IHBD) and gall bladder and biliary tract (GBTC) cancers.
2017
Circulating copper and zinc levels and risk of hepatobiliary cancers in Europeans / Stepien, M., Hughes, D.J., Hybsier, S., Bamia, C., Tjønneland, A., Overvad, K., Affret, A., His, M., Boutron Ruault, M.C., Katzke, V., Kühn, T., Aleksandrova, K., Trichopoulou, A., Lagiou, P., Orfanos, P., Palli, D., Sieri, S., Tumino, R., Ricceri, F., Panico, S., et al.. - In: BRITISH JOURNAL OF CANCER. - ISSN 1532-1827. - 116:5(2017), p. 688-696. [10.1038/bjc.2017.1]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/673927
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