In humans, low socioeconomic status (SES) across the life course is associated with greater diurnal cortisol production, increased inflammatory activity and higher circulating antibodies for several pathogens, all suggesting a dampened immune response. Recent evidence suggests that DNA methylation of pro-inflammatory genes may be implicated in the biological embedding of the social environment.

Life-course socioeconomic status and DNA methylation of genes regulating inflammation / Stringhini, S., Polidoro, S., Sacerdote, C., Kelly, R.S., van Veldhoven, K., Agnoli, C., Grioni, S., Tumino, R., Giurdanella, M.C., Panico, S., Mattiello, A., Palli, D., Masala, G., Gallo, V., Castagné, R., Paccaud, F., Campanella, G., Chadeau Hyam, M., Vineis, P.. - In: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. - ISSN 0300-5771. - 44:4(2015), p. 1320-30. [10.1093/ije/dyv060]

Life-course socioeconomic status and DNA methylation of genes regulating inflammation

PANICO, SALVATORE;
2015

Abstract

In humans, low socioeconomic status (SES) across the life course is associated with greater diurnal cortisol production, increased inflammatory activity and higher circulating antibodies for several pathogens, all suggesting a dampened immune response. Recent evidence suggests that DNA methylation of pro-inflammatory genes may be implicated in the biological embedding of the social environment.
2015
Life-course socioeconomic status and DNA methylation of genes regulating inflammation / Stringhini, S., Polidoro, S., Sacerdote, C., Kelly, R.S., van Veldhoven, K., Agnoli, C., Grioni, S., Tumino, R., Giurdanella, M.C., Panico, S., Mattiello, A., Palli, D., Masala, G., Gallo, V., Castagné, R., Paccaud, F., Campanella, G., Chadeau Hyam, M., Vineis, P.. - In: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. - ISSN 0300-5771. - 44:4(2015), p. 1320-30. [10.1093/ije/dyv060]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/650518
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