About 60% of ovarian cancers are diagnosed at late stage, when 5-year survival is less than 30% in contrast to 90% for local disease. This has prompted search for early detection biomarkers. For initial testing, specimens taken months or years before ovarian cancer diagnosis are the best source of information to evaluate early detection biomarkers. Here we evaluate the most promising ovarian cancer screening biomarkers in prospectively collected samples from the European Prospective Investigation into Cancer and Nutrition study.

A Prospective Evaluation of Early Detection Biomarkers for Ovarian Cancer in the European EPIC Cohort / Terry, K.L., Schock, H., Fortner, R.T., Hüsing, A., Fichorova, R.N., Yamamoto, H.S., Vitonis, A.F., Johnson, T., Overvad, K., Tjønneland, A., Boutron Ruault, M.C., Mesrine, S., Severi, G., Dossus, L., Rinaldi, S., Boeing, H., Benetou, V., Lagiou, P., Trichopoulou, A., Krogh, V., et al.. - In: CLINICAL CANCER RESEARCH. - ISSN 1078-0432. - 22:18(2016), p. 4664-75. [10.1158/1078-0432.CCR-16-0316]

A Prospective Evaluation of Early Detection Biomarkers for Ovarian Cancer in the European EPIC Cohort

PANICO, SALVATORE;
2016

Abstract

About 60% of ovarian cancers are diagnosed at late stage, when 5-year survival is less than 30% in contrast to 90% for local disease. This has prompted search for early detection biomarkers. For initial testing, specimens taken months or years before ovarian cancer diagnosis are the best source of information to evaluate early detection biomarkers. Here we evaluate the most promising ovarian cancer screening biomarkers in prospectively collected samples from the European Prospective Investigation into Cancer and Nutrition study.
2016
A Prospective Evaluation of Early Detection Biomarkers for Ovarian Cancer in the European EPIC Cohort / Terry, K.L., Schock, H., Fortner, R.T., Hüsing, A., Fichorova, R.N., Yamamoto, H.S., Vitonis, A.F., Johnson, T., Overvad, K., Tjønneland, A., Boutron Ruault, M.C., Mesrine, S., Severi, G., Dossus, L., Rinaldi, S., Boeing, H., Benetou, V., Lagiou, P., Trichopoulou, A., Krogh, V., et al.. - In: CLINICAL CANCER RESEARCH. - ISSN 1078-0432. - 22:18(2016), p. 4664-75. [10.1158/1078-0432.CCR-16-0316]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/650507
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