Obesity is positively associated with colorectal cancer. Recently, body size subtypes categorised by the prevalence of hyperinsulinaemia have been defined, and metabolically healthy overweight/obese individuals (without hyperinsulinaemia) have been suggested to be at lower risk of cardiovascular disease than their metabolically unhealthy (hyperinsulinaemic) overweight/obese counterparts. Whether similarly variable relationships exist for metabolically defined body size phenotypes and colorectal cancer risk is unknown.

A Nested Case-Control Study of Metabolically Defined Body Size Phenotypes and Risk of Colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) / Murphy, N., Cross, A.J., Abubakar, M., Jenab, M., Aleksandrova, K., Boutron Ruault, M.C., Dossus, L., Racine, A., Kühn, T., Katzke, V.A., Tjønneland, A., Petersen, K.E.N., Overvad, K., Quirós, J.R., Jakszyn, P., Molina Montes, E., Dorronsoro, M., Huerta, J.M., Barricarte, A., Khaw, K.T., et al.. - In: PLOS MEDICINE. - ISSN 1549-1676. - 13:4(2016), p. e1001988. [10.1371/journal.pmed.1001988]

A Nested Case-Control Study of Metabolically Defined Body Size Phenotypes and Risk of Colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC)

PANICO, SALVATORE;
2016

Abstract

Obesity is positively associated with colorectal cancer. Recently, body size subtypes categorised by the prevalence of hyperinsulinaemia have been defined, and metabolically healthy overweight/obese individuals (without hyperinsulinaemia) have been suggested to be at lower risk of cardiovascular disease than their metabolically unhealthy (hyperinsulinaemic) overweight/obese counterparts. Whether similarly variable relationships exist for metabolically defined body size phenotypes and colorectal cancer risk is unknown.
2016
A Nested Case-Control Study of Metabolically Defined Body Size Phenotypes and Risk of Colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) / Murphy, N., Cross, A.J., Abubakar, M., Jenab, M., Aleksandrova, K., Boutron Ruault, M.C., Dossus, L., Racine, A., Kühn, T., Katzke, V.A., Tjønneland, A., Petersen, K.E.N., Overvad, K., Quirós, J.R., Jakszyn, P., Molina Montes, E., Dorronsoro, M., Huerta, J.M., Barricarte, A., Khaw, K.T., et al.. - In: PLOS MEDICINE. - ISSN 1549-1676. - 13:4(2016), p. e1001988. [10.1371/journal.pmed.1001988]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/650501
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