Elevated levels of C-reactive protein (CRP, determined by a high-sensitivity assay) indicate low-grade inflammation which is implicated in many age-related disorders. Epigenetic studies on CRP might discover molecular mechanisms underlying CRP regulation. We aimed to identify DNA methylation sites related to CRP concentrations in cells and tissues regulating low-grade inflammation.

Epigenetic Signatures at AQP3 and SOCS3 Engage in Low-Grade Inflammation across Different Tissues / Marzi, C., Holdt, L.M., Fiorito, G., Tsai, P.C., Kretschmer, A., Wahl, S., Guarrera, S., Teupser, D., Spector, T.D., Iacoviello, L., Sacerdote, C., Strauch, K., Lee, S., Thasler, W.E., Peters, A., Thorand, B., Wolf, P., Prokisch, H., Tumino, R., Gieger, C., et al.. - In: PLOS ONE. - ISSN 1932-6203. - 11:11(2016), p. e0166015. [10.1371/journal.pone.0166015]

Epigenetic Signatures at AQP3 and SOCS3 Engage in Low-Grade Inflammation across Different Tissues

PANICO, SALVATORE;
2016

Abstract

Elevated levels of C-reactive protein (CRP, determined by a high-sensitivity assay) indicate low-grade inflammation which is implicated in many age-related disorders. Epigenetic studies on CRP might discover molecular mechanisms underlying CRP regulation. We aimed to identify DNA methylation sites related to CRP concentrations in cells and tissues regulating low-grade inflammation.
2016
Epigenetic Signatures at AQP3 and SOCS3 Engage in Low-Grade Inflammation across Different Tissues / Marzi, C., Holdt, L.M., Fiorito, G., Tsai, P.C., Kretschmer, A., Wahl, S., Guarrera, S., Teupser, D., Spector, T.D., Iacoviello, L., Sacerdote, C., Strauch, K., Lee, S., Thasler, W.E., Peters, A., Thorand, B., Wolf, P., Prokisch, H., Tumino, R., Gieger, C., et al.. - In: PLOS ONE. - ISSN 1932-6203. - 11:11(2016), p. e0166015. [10.1371/journal.pone.0166015]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/650493
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 16
  • ???jsp.display-item.citation.isi??? 16
social impact