Current guidelines recommend a stepwise approach for pharmacological therapy aimed to achieve and maintain asthma control. Despite these recommendations, at least 50% of patients continue to be uncontrolled with risk of asthma exacerbations that can often be serious and are associated with deterioration of quality of life. In recent years, the interest in anticholinergic bronchodilators, which have been primarily used in the treatment of chronic obstructive pulmonary disease, has increased patients with uncontrolled asthma. This review analyzes the mechanisms for the proposed clinical use of anticholinergic bronchodilators as an adjunctive therapy in asthma.

Anticholinergic drugs in asthma therapy / D'Amato, Maria; Vitale, Carolina; Molino, Antonio; Lanza, Maurizia; D'Amato, Gennaro. - In: CURRENT OPINION IN PULMONARY MEDICINE. - ISSN 1070-5287. - (2016), p. 1. [10.1097/MCP.0000000000000344]

Anticholinergic drugs in asthma therapy

VITALE, CAROLINA;MOLINO, ANTONIO;LANZA, MAURIZIA;D'AMATO, Gennaro
2016

Abstract

Current guidelines recommend a stepwise approach for pharmacological therapy aimed to achieve and maintain asthma control. Despite these recommendations, at least 50% of patients continue to be uncontrolled with risk of asthma exacerbations that can often be serious and are associated with deterioration of quality of life. In recent years, the interest in anticholinergic bronchodilators, which have been primarily used in the treatment of chronic obstructive pulmonary disease, has increased patients with uncontrolled asthma. This review analyzes the mechanisms for the proposed clinical use of anticholinergic bronchodilators as an adjunctive therapy in asthma.
2016
Anticholinergic drugs in asthma therapy / D'Amato, Maria; Vitale, Carolina; Molino, Antonio; Lanza, Maurizia; D'Amato, Gennaro. - In: CURRENT OPINION IN PULMONARY MEDICINE. - ISSN 1070-5287. - (2016), p. 1. [10.1097/MCP.0000000000000344]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/649886
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