Amphiphilic poly(ethylene oxide) - polypropylene oxide) triblock copolymers are very appealing materials for biomedical application since they can be easily injected as liquid at room temperature while they produce a gel when in the body. On the other hand, these materials no longer hold the gel state when in presence of solvent (as physiological solutions) due to the dilution of the system. To overcome these limitations Cohn and coworkers(1) have synthesized a novel thermo-responsive systems by extending the chain of the commercially available PEO-PPO copolymer named Fi27. The aim of this study was to evaluate the effect of the chemical modification on the macroscopic, Theological, and microscopic, transport, properties of these new materials.
Micro and macro characterization of PEO-PPO-PEO triblocks hydrogels / Fusco, S; Borzacchiello, A.; Cohn, D.; Netti, PAOLO ANTONIO. - In: MACROMOLECULAR SYMPOSIA. - ISSN 1022-1360. - 266:1(2008), pp. 92-95. (Intervento presentato al convegno Biohydrogels tenutosi a Viareggio (ITALY)) [10.1002/masy.200850617].
Micro and macro characterization of PEO-PPO-PEO triblocks hydrogels
NETTI, PAOLO ANTONIO
2008
Abstract
Amphiphilic poly(ethylene oxide) - polypropylene oxide) triblock copolymers are very appealing materials for biomedical application since they can be easily injected as liquid at room temperature while they produce a gel when in the body. On the other hand, these materials no longer hold the gel state when in presence of solvent (as physiological solutions) due to the dilution of the system. To overcome these limitations Cohn and coworkers(1) have synthesized a novel thermo-responsive systems by extending the chain of the commercially available PEO-PPO copolymer named Fi27. The aim of this study was to evaluate the effect of the chemical modification on the macroscopic, Theological, and microscopic, transport, properties of these new materials.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
