An analytical solution for Low-Density Lipoprotein transport through an arterial wall under hyperthermia conditions is established in this work. A four-layer model is used to characterize the arterial wall. Transport governing equations are obtained as a combination between Staverman-Kedem-Katchalsky membrane equations and volume-averaged porous media equations. Temperature and solute transport fields are coupled by means of Ludwig-Soret effect. Results are in excellent agreement with numerical and analytical literature data under isothermal conditions, and with numerical literature data for the hyperthermia case. Effects of hypertension combined with hyperthermia, are also analyzed in this work.

Low-Density Lipoprotein Transport through an Arterial Wall under Hyperthermia and Hypertension Conditions – An Analytical Solution / Iasiello, Marcello; Vafai, K.; Andreozzi, Assunta; Bianco, Nicola. - In: JOURNAL OF BIOMECHANICS. - ISSN 0021-9290. - 49:2(2016), pp. 193-204. [10.1016/j.jbiomech.2015.12.015]

Low-Density Lipoprotein Transport through an Arterial Wall under Hyperthermia and Hypertension Conditions – An Analytical Solution

IASIELLO, MARCELLO;ANDREOZZI, ASSUNTA;BIANCO, NICOLA
2016

Abstract

An analytical solution for Low-Density Lipoprotein transport through an arterial wall under hyperthermia conditions is established in this work. A four-layer model is used to characterize the arterial wall. Transport governing equations are obtained as a combination between Staverman-Kedem-Katchalsky membrane equations and volume-averaged porous media equations. Temperature and solute transport fields are coupled by means of Ludwig-Soret effect. Results are in excellent agreement with numerical and analytical literature data under isothermal conditions, and with numerical literature data for the hyperthermia case. Effects of hypertension combined with hyperthermia, are also analyzed in this work.
2016
Low-Density Lipoprotein Transport through an Arterial Wall under Hyperthermia and Hypertension Conditions – An Analytical Solution / Iasiello, Marcello; Vafai, K.; Andreozzi, Assunta; Bianco, Nicola. - In: JOURNAL OF BIOMECHANICS. - ISSN 0021-9290. - 49:2(2016), pp. 193-204. [10.1016/j.jbiomech.2015.12.015]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/635540
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