A highly convergent multistep process incorporating an aza-Achmatowicz rearrangement has been described, selectively providing enantiomerically pure bicyclic (dihydro)furans 9 and 18 as well as the tricyclic dihydropyridinone 23 from acyclic starting materials after up to eight sequential synthetic transformations in one step.

Beyond Achmatowicz reaction: DDQ-mediated chemo- and stereoconvergent domino-one pot cyclization/rearrangement of bis-thioenol ether-containing chiral building blocks

GUARAGNA, ANNALISA;D'ERRICO, STEFANO;PALUMBO, GIOVANNI;D'ALONZO, DANIELE
2014

Abstract

A highly convergent multistep process incorporating an aza-Achmatowicz rearrangement has been described, selectively providing enantiomerically pure bicyclic (dihydro)furans 9 and 18 as well as the tricyclic dihydropyridinone 23 from acyclic starting materials after up to eight sequential synthetic transformations in one step.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11588/625017
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