The essential oils from Origanum dictamnus, Origanum libanoticum and Origanum microphyllum were analyzed by GC-​MS, finding carvacrol, p-​cymene, linalool, γ-​terpinene and terpinen-​4-​ol as major components. The antioxidant activity by the DPPH and FRAP tests and the antiproliferative activity against two human cancer cell lines, LoVo and HepG2, were investigated, showing that the essential oil of O. dictamnus was statistically the most inhibitory on both the cell lines, while all the oils exerted a weak antioxidant activity. Furthermore, the samples were tested against 10 Gram-​neg. and Gram-​pos. bacteria; all the oils were active on Gram-​pos. bacteria but O. dictamnus essential oil was the most effective (MIC = 25-​50 μg​/mL)​, showing also a good activity against the Gram-​neg. Escherichia coli (MIC = 50 μg​/mL)​. Data suggest that these essential oils and particularly O. dictamnus oil could be used as valuable new flavors with functional properties for food or nutraceutical products.

Composition, antibacterial, antioxidant and antiproliferative activities of essential oils from three Origanum species growing wild in Lebanon and Greece / Marrelli, Mariangela; Conforti, Filomena; Formisano, Carmen; Rigano, Daniela; Arnold, Nelly Apostolides; Menichini, Francesco; Senatore, Felice. - In: NATURAL PRODUCT RESEARCH. - ISSN 1478-6419. - 30:6(2016), pp. 735-739. [10.1080/14786419.2015.1040993]

Composition, antibacterial, antioxidant and antiproliferative activities of essential oils from three Origanum species growing wild in Lebanon and Greece

FORMISANO, CARMEN;RIGANO, DANIELA
;
SENATORE, FELICE
2016

Abstract

The essential oils from Origanum dictamnus, Origanum libanoticum and Origanum microphyllum were analyzed by GC-​MS, finding carvacrol, p-​cymene, linalool, γ-​terpinene and terpinen-​4-​ol as major components. The antioxidant activity by the DPPH and FRAP tests and the antiproliferative activity against two human cancer cell lines, LoVo and HepG2, were investigated, showing that the essential oil of O. dictamnus was statistically the most inhibitory on both the cell lines, while all the oils exerted a weak antioxidant activity. Furthermore, the samples were tested against 10 Gram-​neg. and Gram-​pos. bacteria; all the oils were active on Gram-​pos. bacteria but O. dictamnus essential oil was the most effective (MIC = 25-​50 μg​/mL)​, showing also a good activity against the Gram-​neg. Escherichia coli (MIC = 50 μg​/mL)​. Data suggest that these essential oils and particularly O. dictamnus oil could be used as valuable new flavors with functional properties for food or nutraceutical products.
2016
Composition, antibacterial, antioxidant and antiproliferative activities of essential oils from three Origanum species growing wild in Lebanon and Greece / Marrelli, Mariangela; Conforti, Filomena; Formisano, Carmen; Rigano, Daniela; Arnold, Nelly Apostolides; Menichini, Francesco; Senatore, Felice. - In: NATURAL PRODUCT RESEARCH. - ISSN 1478-6419. - 30:6(2016), pp. 735-739. [10.1080/14786419.2015.1040993]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/619884
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