Lipoprotein-associated phospholipase A2 (Lp-PLA2) has been hypothesized to be involved in atherogenesis through pathways related to inflammation. Darapladib is an oral, selective inhibitor of the Lp-PLA2 enzyme.

Effect of darapladib on major coronary events after an acute coronary syndrome: the SOLID-TIMI 52 randomized clinical trial / O'Donoghue, M.l., Braunwald, E., White, H.D., Steen, D.P., Lukas, M.A., Tarka, E., Steg, P.G., Hochman, J.S., Bode, C., Maggioni, A.P., Im, K., Shannon, J.B., Davies, R.Y., Murphy, S.A., Crugnale, S.E., Wiviott, S.D., Bonaca, M.P., Watson, D.F., Weaver, W.D., Serruys, P.W., et al.. - In: JAMA. - ISSN 0098-7484. - 312:10(2014), pp. 1006-1015. [10.1001/jama.2014.11061]

Effect of darapladib on major coronary events after an acute coronary syndrome: the SOLID-TIMI 52 randomized clinical trial

ESPOSITO, GIOVANNI;
2014

Abstract

Lipoprotein-associated phospholipase A2 (Lp-PLA2) has been hypothesized to be involved in atherogenesis through pathways related to inflammation. Darapladib is an oral, selective inhibitor of the Lp-PLA2 enzyme.
2014
Effect of darapladib on major coronary events after an acute coronary syndrome: the SOLID-TIMI 52 randomized clinical trial / O'Donoghue, M.l., Braunwald, E., White, H.D., Steen, D.P., Lukas, M.A., Tarka, E., Steg, P.G., Hochman, J.S., Bode, C., Maggioni, A.P., Im, K., Shannon, J.B., Davies, R.Y., Murphy, S.A., Crugnale, S.E., Wiviott, S.D., Bonaca, M.P., Watson, D.F., Weaver, W.D., Serruys, P.W., et al.. - In: JAMA. - ISSN 0098-7484. - 312:10(2014), pp. 1006-1015. [10.1001/jama.2014.11061]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/614331
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