Lipoprotein-associated phospholipase A2 (Lp-PLA2) has been hypothesized to be involved in atherogenesis through pathways related to inflammation. Darapladib is an oral, selective inhibitor of the Lp-PLA2 enzyme.

Effect of darapladib on major coronary events after an acute coronary syndrome: the SOLID-TIMI 52 randomized clinical trial / O'Donoghue, Ml; Braunwald, Eugene; White, Harvey D; Steen, Dylan P; Lukas, Mary Ann; Tarka, Elizabeth; Steg, P. Gabriel; Hochman, Judith S; Bode, Christoph; Maggioni, Aldo P; Im, Kyungah; Shannon, Jennifer B; Davies, Richard Y; Murphy, Sabina A; Crugnale, Sharon E; Wiviott, Stephen D; Bonaca, Marc P; Watson, David F; Weaver, W. Douglas; Serruys, Patrick W; Cannon, Christopher P; Esposito, Giovanni; Steen Dylan, L.. - In: JAMA. - ISSN 0098-7484. - 312:10(2014), pp. 1006-1015. [10.1001/jama.2014.11061]

Effect of darapladib on major coronary events after an acute coronary syndrome: the SOLID-TIMI 52 randomized clinical trial

ESPOSITO, GIOVANNI;
2014

Abstract

Lipoprotein-associated phospholipase A2 (Lp-PLA2) has been hypothesized to be involved in atherogenesis through pathways related to inflammation. Darapladib is an oral, selective inhibitor of the Lp-PLA2 enzyme.
2014
Effect of darapladib on major coronary events after an acute coronary syndrome: the SOLID-TIMI 52 randomized clinical trial / O'Donoghue, Ml; Braunwald, Eugene; White, Harvey D; Steen, Dylan P; Lukas, Mary Ann; Tarka, Elizabeth; Steg, P. Gabriel; Hochman, Judith S; Bode, Christoph; Maggioni, Aldo P; Im, Kyungah; Shannon, Jennifer B; Davies, Richard Y; Murphy, Sabina A; Crugnale, Sharon E; Wiviott, Stephen D; Bonaca, Marc P; Watson, David F; Weaver, W. Douglas; Serruys, Patrick W; Cannon, Christopher P; Esposito, Giovanni; Steen Dylan, L.. - In: JAMA. - ISSN 0098-7484. - 312:10(2014), pp. 1006-1015. [10.1001/jama.2014.11061]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/614331
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