The prevalence of obesity is increasing among children/adolescents. Subtle cardiovascular abnormalities, responsible for a higher mortality later in life, have been reported in obese children/adolescents. The aims of the study were to evaluate cardiovascular autonomic regulation, by means of spectrum analysis of R-R interval variability, and myocardial function, by means of standard and tissue Doppler echocardiography, in a group of non-hypertensive asymptomatic obese children and adolescents; furthermore, the influence of insulin resistance was tested.

Subclinical myocardial dysfunction and cardiac autonomic dysregulation are closely associated in obese children and adolescents: the potential role of insulin resistance / Cozzolino, Domenico; Grandone, Anna; Cittadini, Antonio; Palmiero, Giuseppe; Esposito, Giovanni; DE BELLIS, Annamaria; Furlan, Raffaello; Perrotta, Silverio; Perrone, Laura; Torella, Daniele; MIRAGLIA DEL GIUDICE, Emanuele. - In: PLOS ONE. - ISSN 1932-6203. - 10:4(2015), pp. 1-13. [10.1371/journal.pone.0123916]

Subclinical myocardial dysfunction and cardiac autonomic dysregulation are closely associated in obese children and adolescents: the potential role of insulin resistance

COZZOLINO, DOMENICO;CITTADINI, ANTONIO;PALMIERO, GIUSEPPE;ESPOSITO, GIOVANNI;DE BELLIS, ANNAMARIA;PERROTTA, SILVERIO;TORELLA, DANIELE;MIRAGLIA DEL GIUDICE, EMANUELE
2015

Abstract

The prevalence of obesity is increasing among children/adolescents. Subtle cardiovascular abnormalities, responsible for a higher mortality later in life, have been reported in obese children/adolescents. The aims of the study were to evaluate cardiovascular autonomic regulation, by means of spectrum analysis of R-R interval variability, and myocardial function, by means of standard and tissue Doppler echocardiography, in a group of non-hypertensive asymptomatic obese children and adolescents; furthermore, the influence of insulin resistance was tested.
2015
Subclinical myocardial dysfunction and cardiac autonomic dysregulation are closely associated in obese children and adolescents: the potential role of insulin resistance / Cozzolino, Domenico; Grandone, Anna; Cittadini, Antonio; Palmiero, Giuseppe; Esposito, Giovanni; DE BELLIS, Annamaria; Furlan, Raffaello; Perrotta, Silverio; Perrone, Laura; Torella, Daniele; MIRAGLIA DEL GIUDICE, Emanuele. - In: PLOS ONE. - ISSN 1932-6203. - 10:4(2015), pp. 1-13. [10.1371/journal.pone.0123916]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/614217
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