A case of a 70-year-old man with multiple actinic keratoses and lichenoid lesions on sun-exposed skin areas, is reported. The patient, splenectomised for an idiopathic myelofibrosis, was treated with hydroxyurea. Phototesting, with daily doses of UVA 5 J/cm2 and UVB 60 mJ/cm2 on a fixed skin area for 8 consecutive days, elicited a lichenoid eruption. The interruption of the hydroxyurea treatment together with a careful photoprotection gave rise to an improvement of lichenoid lesions.
Multiple actinic keratoses and lichenoid eruption induced by hydroxyurea and sun exposure
MONFRECOLA, GIUSEPPE;
2001
Abstract
A case of a 70-year-old man with multiple actinic keratoses and lichenoid lesions on sun-exposed skin areas, is reported. The patient, splenectomised for an idiopathic myelofibrosis, was treated with hydroxyurea. Phototesting, with daily doses of UVA 5 J/cm2 and UVB 60 mJ/cm2 on a fixed skin area for 8 consecutive days, elicited a lichenoid eruption. The interruption of the hydroxyurea treatment together with a careful photoprotection gave rise to an improvement of lichenoid lesions.File in questo prodotto:
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