A group of 88 patients affected with vitiligo were treated by epidermoabrasion and daily applications of 5-fluorouracil (5-FU) or cyclosporin A (CyA) with occlusive dressing for 15 days. Repigmentation was observed in 70% patients treated with 5-FU and in 5,5% of patients treated with CyA. Repigmentation appeared 4-8 weeks after suspension of treatment and was complete after 5-6 months. No side effects were observed. The action of the two drugs is discussed.

VITILIGINE A PICCOLE CHIAZZE: ABRASIONE EPIDERMICA E 5-FU VERSUS ABRASIONE EPIDERMICA E CYA

DELFINO, MARIO;MONFRECOLA, GIUSEPPE
1991

Abstract

A group of 88 patients affected with vitiligo were treated by epidermoabrasion and daily applications of 5-fluorouracil (5-FU) or cyclosporin A (CyA) with occlusive dressing for 15 days. Repigmentation was observed in 70% patients treated with 5-FU and in 5,5% of patients treated with CyA. Repigmentation appeared 4-8 weeks after suspension of treatment and was complete after 5-6 months. No side effects were observed. The action of the two drugs is discussed.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11588/607232
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