A controlled trial of topical photochemotherapy of plaque-type psoriasis using hematoporphyrin derivative (HPD) in combination with red light (590-700 nm) was performed on 8 patients. For each patient HPD (1%) in N-methylpyrrolidone was applied on one psoriatic patch, only the vehicle being applied on the control one. Both patches were daily irradiated with incoherent red light (60 J/cm2/day) for a week. Comparative evaluation of clinical and histologic results are discussed.
Topical administration of hematoporphyrin derivative and red light irradiation. A therapeutic approach in psoriasis / Monfrecola, Giuseppe; Mangone, S; Procaccini, Em; Santoianni, Pietro. - In: GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA. - ISSN 0392-0488. - 123:12(1988), pp. 671-674.
Topical administration of hematoporphyrin derivative and red light irradiation. A therapeutic approach in psoriasis
MONFRECOLA, GIUSEPPE;SANTOIANNI, PIETRO
1988
Abstract
A controlled trial of topical photochemotherapy of plaque-type psoriasis using hematoporphyrin derivative (HPD) in combination with red light (590-700 nm) was performed on 8 patients. For each patient HPD (1%) in N-methylpyrrolidone was applied on one psoriatic patch, only the vehicle being applied on the control one. Both patches were daily irradiated with incoherent red light (60 J/cm2/day) for a week. Comparative evaluation of clinical and histologic results are discussed.| File | Dimensione | Formato | |
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