A first solid phase approach to obtain monosubstituted CD conjugates to different labels has been developed. A new solid support has been designed to get a variety of C-6 monofunctionalized CDs (alpha, beta, Me beta CD and HP beta CD) covalently linked through a phosphodiester bridge to different labels, in highly pure form and under very mild detachment conditions.
A novel synthetic strategy for mono-substituted cyclodextrin derivatives
DI FABIO, GIOVANNI;D'ONOFRIO, JENNIFER;ZARRELLI, ARMANDO;DE NAPOLI, LORENZO
2012
Abstract
A first solid phase approach to obtain monosubstituted CD conjugates to different labels has been developed. A new solid support has been designed to get a variety of C-6 monofunctionalized CDs (alpha, beta, Me beta CD and HP beta CD) covalently linked through a phosphodiester bridge to different labels, in highly pure form and under very mild detachment conditions.File in questo prodotto:
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