This paper reports on gastrointestinal sensitivity, including on the role of refluxate volume on the perception of reflux symptoms; experimental pain models that mimic mechanisms and symptoms of pain associated with esophageal diseases; the potential role of the acid receptor TRPV1 in the genesis of gastroesophageal reflux disease (GERD) symptoms; and roles for ATP and the purine and pyrimidine receptor subfamilies P1, P2X, and P2Y in the pathogenesis of GERD symptoms.

Gastrointestinal sensitivity and gastroesophageal reflux disease / Altomare, A., Guarino, M.p., Emerenziani, S., Cicala, M., Drewes, A.m., Krarup, A.l., Brock, C., Lottrup, C., Fr?kjaer, J.b., Souza, R.f., Nardone, G.A.P., Compare, D.. - In: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. - ISSN 0077-8923. - 1300:(2013), pp. 80-95. [10.1111/nyas.12236]

Gastrointestinal sensitivity and gastroesophageal reflux disease.

NARDONE, GERARDO ANTONIO PIO;COMPARE, DEBORA
2013

Abstract

This paper reports on gastrointestinal sensitivity, including on the role of refluxate volume on the perception of reflux symptoms; experimental pain models that mimic mechanisms and symptoms of pain associated with esophageal diseases; the potential role of the acid receptor TRPV1 in the genesis of gastroesophageal reflux disease (GERD) symptoms; and roles for ATP and the purine and pyrimidine receptor subfamilies P1, P2X, and P2Y in the pathogenesis of GERD symptoms.
2013
Gastrointestinal sensitivity and gastroesophageal reflux disease / Altomare, A., Guarino, M.p., Emerenziani, S., Cicala, M., Drewes, A.m., Krarup, A.l., Brock, C., Lottrup, C., Fr?kjaer, J.b., Souza, R.f., Nardone, G.A.P., Compare, D.. - In: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. - ISSN 0077-8923. - 1300:(2013), pp. 80-95. [10.1111/nyas.12236]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/577121
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