Context: Micro-RNA have emerged as an important class of short endogenous RNA that act as posttranscriptional regulators of gene expression and are constantly deregulated in human cancer. MiR-1 has been found down-regulated in lung, colon, and prostate cancer. Objectives: In this study, we investigated the possible role of miR-1 in thyroid carcinogenesis. Design: We have analyzed miR-1 expression in a panel of thyroid neoplasias including benign and malignant lesions and searched for miR-1 targets.

MiR-1 Is a Tumor Suppressor in Thyroid Carcinogenesis Targeting CCND2, CXCR4, and SDF-1{alpha} / Leone, V., D'Angelo, D., Rubio, I., de Freitas, P.m., Federico, A., Colamaio, M., Pallante, P., Medeiros Neto, G., Fusco, A.. - In: THE JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM. - ISSN 0021-972X. - 96:9(2011), pp. 1388-1398. [10.1210/jc.2011-0345]

MiR-1 Is a Tumor Suppressor in Thyroid Carcinogenesis Targeting CCND2, CXCR4, and SDF-1{alpha}.

FUSCO, ALFREDO
2011

Abstract

Context: Micro-RNA have emerged as an important class of short endogenous RNA that act as posttranscriptional regulators of gene expression and are constantly deregulated in human cancer. MiR-1 has been found down-regulated in lung, colon, and prostate cancer. Objectives: In this study, we investigated the possible role of miR-1 in thyroid carcinogenesis. Design: We have analyzed miR-1 expression in a panel of thyroid neoplasias including benign and malignant lesions and searched for miR-1 targets.
2011
MiR-1 Is a Tumor Suppressor in Thyroid Carcinogenesis Targeting CCND2, CXCR4, and SDF-1{alpha} / Leone, V., D'Angelo, D., Rubio, I., de Freitas, P.m., Federico, A., Colamaio, M., Pallante, P., Medeiros Neto, G., Fusco, A.. - In: THE JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM. - ISSN 0021-972X. - 96:9(2011), pp. 1388-1398. [10.1210/jc.2011-0345]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/575492
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