Microfluidics has been widely exploited to perform chemical reactions under highly controlled environment (physical and chemical). In fact, microfluidics controls the size and shape of the particles and scales down the time of the diffusion, mixing and reaction. This paper reports a novel attempt to crosslink nonspherical particles (NSP) in one-step process. Here we perform crosslink and hardening reaction of gelatin by formaldehyde inside a simple microfluidic reactor by immiscibile liquid mixing within nanoliter plugbased microfluidic device. In doing so, we create multi-component droplets that along the channel are first mixed and then hardened and crosslinked. The collected particles displays a dispersion lower than 1%
Non-spherical gelatin particle in two phases microfluidic system / Giuseppina, Simone; Netti, PAOLO ANTONIO. - In: MICROELECTRONIC ENGINEERING. - ISSN 0167-9317. - 111:(2013), pp. 339-342. [10.1016/j.mee.2013.02.085]
Non-spherical gelatin particle in two phases microfluidic system
NETTI, PAOLO ANTONIO
2013
Abstract
Microfluidics has been widely exploited to perform chemical reactions under highly controlled environment (physical and chemical). In fact, microfluidics controls the size and shape of the particles and scales down the time of the diffusion, mixing and reaction. This paper reports a novel attempt to crosslink nonspherical particles (NSP) in one-step process. Here we perform crosslink and hardening reaction of gelatin by formaldehyde inside a simple microfluidic reactor by immiscibile liquid mixing within nanoliter plugbased microfluidic device. In doing so, we create multi-component droplets that along the channel are first mixed and then hardened and crosslinked. The collected particles displays a dispersion lower than 1%I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.