A new synthetic strategy to get the PNA–3′DNA linker with the monomethoxytrityl (Mmt) group as temporary protection of the backbone to be used for the synthesis of PNA/DNA chimeras was employed and a convenient strategy to obtain Mmt PNA monomers was developed. The synthetic strategies take advantage of the introduction of the acid-labile Mmt-protecting group in the first step.
Titolo: | New synthesis of PNA-3'DNA linker monomers, useful building blocks to obtain PNA/DNA chimeras |
Autori: | |
Data di pubblicazione: | 2004 |
Rivista: | |
Abstract: | A new synthetic strategy to get the PNA–3′DNA linker with the monomethoxytrityl (Mmt) group as temporary protection of the backbone to be used for the synthesis of PNA/DNA chimeras was employed and a convenient strategy to obtain Mmt PNA monomers was developed. The synthetic strategies take advantage of the introduction of the acid-labile Mmt-protecting group in the first step. |
Handle: | http://hdl.handle.net/11588/565526 |
Appare nelle tipologie: | 1.1 Articolo in rivista |
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