Why nature selected 5,6-dihydroxyindole-2-carboxylic acid (DHICA) to synthesize (photo)protective eumelanin pigments is an enigma. Synthetic DHICA eumelanin has now been shown to be a highly efficient free-radical scavenger in the solid state, which is due to a conformationally interrupted π-electron network associated with atypical optical, paramagnetic, and aggregation properties.

Atypical Structural and pi-​Electron Features of a Melanin Polymer That Lead to Superior Free-​Radical-​Scavenging Properties

PANZELLA, LUCIA;D'ERRICO, GERARDINO;Della Vecchia, Nicola Fyodor;NAPOLITANO, ALESSANDRA;CARFAGNA, COSIMO;D'ISCHIA, MARCO
2013

Abstract

Why nature selected 5,6-dihydroxyindole-2-carboxylic acid (DHICA) to synthesize (photo)protective eumelanin pigments is an enigma. Synthetic DHICA eumelanin has now been shown to be a highly efficient free-radical scavenger in the solid state, which is due to a conformationally interrupted π-electron network associated with atypical optical, paramagnetic, and aggregation properties.
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/565348
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 221
  • ???jsp.display-item.citation.isi??? 220
social impact