Diabetes Resolution Following Bariatric Surgery. Efficacy of Mini Gastric Bypass and Sleeve Gastrectomy

Introduction: Type 2 diabetes mellitus is now a global health priority. The World Health Organization estimates that between 2000 and 2030 the number of diabetic patients will increase by 114%. Although it is worth notice that bariatric surgery could treat the diabetes, little is known about which procedure should be preferred. In order to evaluate the efficacy of sleeve gastrectomy (LSG) and mini gastric by-pass (LMGB), we have designed a comparative study on obese diabetic patients who undergone bariatric surgery. Methods: We have retrospectively evaluated a prospective database of all obese and diabetic patients who have undergone bariatric surgery, between January 2010 and January 2012, including for the analysis 15 LSG and 16 LMGB. We have assessed the efficacy of these procedures in the treatment of diabetes evaluating fasting blood glucose (FPG) and glycosylated haemoglobin (HbA1c) level. Results: Demographical and clinical outcomes were similar between the groups (p = NS). Whereas no statistical difference were found, a trend towards better results was obtained among the patients who undergone LMBG in order to treatment of diabetes. More in details, after one year of follow-up, 87,5% of patients who underwent LMGB and 72,5% of patients who underwent LSG have a normal value of FPG (p = 0,2). Similarly we obtained a normal HbA1c respectively in 75% and 63,3% of patients who underwent LMGB and LSG (p = 0,1). Conclusions: Although more comparative studies are needed to give definitive conclusion, a trend towards better results was obtained aftermini gastric bypass.