Our work shows that rapid caspase-2 activation is essential for Bim induction in neurons subjected to apoptotic stimuli, placing caspase-2 at an apical position in the apoptotic cascade and demonstrating for the first time that a caspase can regulate transcription.
Caspase-2 regulates c-Jun transcriptional activation of Bim in neuron death / Y. Y., Jean; E. M., Ribe; Pero, MARIA ELENA; L. A., Greene; C. M., Troy. - 5:(2012), pp. 22-22. (Intervento presentato al convegno SFN 2012 tenutosi a New Orleans nel 13-17).
Caspase-2 regulates c-Jun transcriptional activation of Bim in neuron death.
PERO, MARIA ELENA;
2012
Abstract
Our work shows that rapid caspase-2 activation is essential for Bim induction in neurons subjected to apoptotic stimuli, placing caspase-2 at an apical position in the apoptotic cascade and demonstrating for the first time that a caspase can regulate transcription.File in questo prodotto:
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