Abstract 1. The in vitro cardiac performance of Octopus vulgaris (Lam) was studied with a new technique that allows perfusion of the ventricle via both the auricles and measurement of coronary efflux. 2. The coronary efflux increases with both preload and Δ load, while the stroke volume increases with preload up to 20 cm of water and decreases with Δ load. 3. The beat rate depends on the preload only. 4. The drugs assayed (acetylcholine, 5-hydroxytryptamine and adrenaline) affect both heart rate and pulse amplitude. The observation that high frequencies are associated with negative inotropic effects explains some results reported in vitro by others.
Invitro Cardiac-performance In Octopus-vulgaris (lam) / L., Foti; I. T., Genoino; Agnisola, Claudio. - In: COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY. C, COMPARATIVE PHARMACOLOGY AND TOXICOLOGY. - ISSN 0742-8413. - STAMPA. - 82:(1985), pp. 483-488. [10.1016/0742-8413(85)90197-5]
Invitro Cardiac-performance In Octopus-vulgaris (lam)
AGNISOLA, CLAUDIO
1985
Abstract
Abstract 1. The in vitro cardiac performance of Octopus vulgaris (Lam) was studied with a new technique that allows perfusion of the ventricle via both the auricles and measurement of coronary efflux. 2. The coronary efflux increases with both preload and Δ load, while the stroke volume increases with preload up to 20 cm of water and decreases with Δ load. 3. The beat rate depends on the preload only. 4. The drugs assayed (acetylcholine, 5-hydroxytryptamine and adrenaline) affect both heart rate and pulse amplitude. The observation that high frequencies are associated with negative inotropic effects explains some results reported in vitro by others.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
