1. The effects of cardiodilatin1–16 and atrial natriuretic factor (ANF) on the coronaryflow in the Octopusvulgaris were studied in vitro by using a preparation of the isolated and perfused systemicheart that produces physiological stroke volumes at physiological load conditions. 2. Both cardiodilatin1–16 and ANF have negative inotropic effects on the isolatedsystemicheart, and cause a significant increase of the coronary stroke volume. 3. The increase of coronary stroke volume is mainly the consequence of the reduction of coronary resistance in the presence of these peptides.
Effects of Cardiodilatin 1-16 and Anf On the Coronary Flow In the Isolated Systemic Heart of Octopus-vulgaris / Agnisola, Claudio; M., Conte; R., Acierno; B., Tota. - In: COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY. A. COMPARATIVE PHYSIOLOGY. - ISSN 0300-9629. - STAMPA. - 94:(1989), pp. 731-733. [10.1016/0300-9629(89)90625-7]
Effects of Cardiodilatin 1-16 and Anf On the Coronary Flow In the Isolated Systemic Heart of Octopus-vulgaris
AGNISOLA, CLAUDIO;
1989
Abstract
1. The effects of cardiodilatin1–16 and atrial natriuretic factor (ANF) on the coronaryflow in the Octopusvulgaris were studied in vitro by using a preparation of the isolated and perfused systemicheart that produces physiological stroke volumes at physiological load conditions. 2. Both cardiodilatin1–16 and ANF have negative inotropic effects on the isolatedsystemicheart, and cause a significant increase of the coronary stroke volume. 3. The increase of coronary stroke volume is mainly the consequence of the reduction of coronary resistance in the presence of these peptides.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
