An easy and efficient strategy to obtain new nucleoside based solid supports in which the nucleoside moieties have been anchored to the solid support through the nucleobase is here proposed. A simple and efficient solid-phase synthesis of 5' and 3'-derivatized uridine analogues has so been developed, following methodologies well established in organic chemistry.
NEW SOLID SUPPORTS LINKING NUCLEOSIDE SCAFFOLDS / de Champdoré, M.; DE NAPOLI, Lorenzo; DI FABIO, Giovanni; Messere, A.; Montesarchio, Daniela; Piccialli, Gennaro. - In: NUCLEOSIDES, NUCLEOTIDES & NUCLEIC ACIDS. - ISSN 1525-7770. - ELETTRONICO. - 22:5-8(2003), pp. 695-697. [10.1081/NCN-120022612]
NEW SOLID SUPPORTS LINKING NUCLEOSIDE SCAFFOLDS
DE NAPOLI, LORENZO;DI FABIO, GIOVANNI;MONTESARCHIO, DANIELA;PICCIALLI, GENNARO
2003
Abstract
An easy and efficient strategy to obtain new nucleoside based solid supports in which the nucleoside moieties have been anchored to the solid support through the nucleobase is here proposed. A simple and efficient solid-phase synthesis of 5' and 3'-derivatized uridine analogues has so been developed, following methodologies well established in organic chemistry.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
