Background and Aim: Carbon dioxide (CO2), contained in carbonated beverages, could increase gastric volume inducing epigastric discomfort and reducing meal intake. We aimed to verify effect of a sugar-free carbonated beverage (CB) preload compared to a CB without CO2 (DCB) and water (W) during a standardized solid (SM) and liquid (LM) meal on gastric volume, gastrointestinal symptoms and eating perceptions. Subjects & Methods: After 300 ml of CB, DCB and W a standardized SM or LM was administered at constant rate (100 kcal/5 min) to ten healthy subjects (4 females, aged 22-30 years; BMI 21-24) on six days in a random order (D1: CB+SM; D2: DCB+SM; D3: W+SM; D4: CB+LM; D5: DCB+LM; D6: W+LM). Gastrointestinal symptoms (bloating and epigastric pain), eating perceptions (desire to eat, hunger, prospective of food consumption) and maximum satiety (MS) as total kcals intake were measured. Total gastric (TGV) and gas volumes by MRI after the beverages and at MS were also evaluated. All data are expressed as mean±SD. Results: Epigastric pain was absent in all experiment. A slight presence of epigastric bloating was found during the SM and LM without differences among beverages. Desire to eat, hunger and prospective of food consumption were not different among beverages and meals. TGV and gas volumes after beverages were significantly higher with CB than DCB and W (TGV: 715±194 ml, 521±83, 478±63, p<0.01; gas: 306±107, 101±29, 107±40, p<0.01). TGV at MS were not different during SM (665±129; 670±147; 664±167; ) and LM (702±252; 674±206; 709±264) respectively. Gas volumes at MS markedly decrease (p<0.01) respect to evalution after beverage and were not different among beverages during SM (20±8, 13±7, 12±5) and LM (15±12, 22±19, 17±17) respectively. Total kcal intakes at MS were not different among beverages during SM (D1: 774±209; D2:837±208; D3: 783±244) and LM (D4: 585±299; D5:585±280; D6: 630±353) respectively. However kcal intakes were higher with SM than LM (p<0.01) independently of beverage preload. Conclusions: A preload of 300 ml of non caloric carbonated beverage does not determine gastrointestinal symptoms and does not affect satiety ratings and eating perceptions in healthy subjects. Other factors as time of administration, volume and carbon dioxide concentration of carbonated beverage must be explored to exclude interference with gastric function
Does the Preload of a Non-Caloric Carbonated Beverage, During a Standardized Solid and Liquid Meal, Affect Gastric Volume and Energy Intake in Healthy Subjects? / Mf, Savarese; E., Nicolai; A., Aragri; G., Sarnelli; E., Atteo; Ig, Savino; Buyckx, M. E.; Cuomo, Rosario. - In: GASTROENTEROLOGY. - ISSN 0016-5085. - ELETTRONICO. - 138:(2010), pp. S44-S44. [10.1016/S0016-5085(10)60203-X]
Does the Preload of a Non-Caloric Carbonated Beverage, During a Standardized Solid and Liquid Meal, Affect Gastric Volume and Energy Intake in Healthy Subjects?
CUOMO, ROSARIO
2010
Abstract
Background and Aim: Carbon dioxide (CO2), contained in carbonated beverages, could increase gastric volume inducing epigastric discomfort and reducing meal intake. We aimed to verify effect of a sugar-free carbonated beverage (CB) preload compared to a CB without CO2 (DCB) and water (W) during a standardized solid (SM) and liquid (LM) meal on gastric volume, gastrointestinal symptoms and eating perceptions. Subjects & Methods: After 300 ml of CB, DCB and W a standardized SM or LM was administered at constant rate (100 kcal/5 min) to ten healthy subjects (4 females, aged 22-30 years; BMI 21-24) on six days in a random order (D1: CB+SM; D2: DCB+SM; D3: W+SM; D4: CB+LM; D5: DCB+LM; D6: W+LM). Gastrointestinal symptoms (bloating and epigastric pain), eating perceptions (desire to eat, hunger, prospective of food consumption) and maximum satiety (MS) as total kcals intake were measured. Total gastric (TGV) and gas volumes by MRI after the beverages and at MS were also evaluated. All data are expressed as mean±SD. Results: Epigastric pain was absent in all experiment. A slight presence of epigastric bloating was found during the SM and LM without differences among beverages. Desire to eat, hunger and prospective of food consumption were not different among beverages and meals. TGV and gas volumes after beverages were significantly higher with CB than DCB and W (TGV: 715±194 ml, 521±83, 478±63, p<0.01; gas: 306±107, 101±29, 107±40, p<0.01). TGV at MS were not different during SM (665±129; 670±147; 664±167; ) and LM (702±252; 674±206; 709±264) respectively. Gas volumes at MS markedly decrease (p<0.01) respect to evalution after beverage and were not different among beverages during SM (20±8, 13±7, 12±5) and LM (15±12, 22±19, 17±17) respectively. Total kcal intakes at MS were not different among beverages during SM (D1: 774±209; D2:837±208; D3: 783±244) and LM (D4: 585±299; D5:585±280; D6: 630±353) respectively. However kcal intakes were higher with SM than LM (p<0.01) independently of beverage preload. Conclusions: A preload of 300 ml of non caloric carbonated beverage does not determine gastrointestinal symptoms and does not affect satiety ratings and eating perceptions in healthy subjects. Other factors as time of administration, volume and carbon dioxide concentration of carbonated beverage must be explored to exclude interference with gastric functionI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
