Pulmonary function tests were performed before and at different times after 250 mg L-Dopa in 12 patients with Parkinson's disease (PD). Six were de-novo patients, the other six patients had been taking L-Dopa over different periods. All patients had an abnormal basal flow-volume loop, which significantly improved only in de-novo patients. This improvement occurred early and was independent on improvement of neurological symptoms. The effect of L-Dopa on pulmonary function could be a useful test in differentiating PD from related extrapyramidal syndromes.
Upper airway muscles dysfunction and levodopa responsiveness in Parkinson's disease / BRESCIA MORRA, Vincenzo; Polverino, M; Luca, Gm; Landi, P; Galdi, M; Campanella, G.. - In: ACTA NEUROLOGICA. - ISSN 0001-6276. - STAMPA. - 14:(1992), pp. 512-518.
Upper airway muscles dysfunction and levodopa responsiveness in Parkinson's disease.
BRESCIA MORRA, VINCENZO;
1992
Abstract
Pulmonary function tests were performed before and at different times after 250 mg L-Dopa in 12 patients with Parkinson's disease (PD). Six were de-novo patients, the other six patients had been taking L-Dopa over different periods. All patients had an abnormal basal flow-volume loop, which significantly improved only in de-novo patients. This improvement occurred early and was independent on improvement of neurological symptoms. The effect of L-Dopa on pulmonary function could be a useful test in differentiating PD from related extrapyramidal syndromes.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
