Epithelioid myoepithelioma of lacrimal gland

we describe a rare case of myoepithelioma of the lacrimal gland composed exclusively of epithelioid cells. Our case showed clear-cut morphological and immunohistochemical features of myoepithelioma that allowed us to easily distinguish it from the above-described benign and malignant proliferation of the lacrimal gland. Myoepithelial cells are generally immunoreactive for S-100, vimentin, cytokeratin, desmin, m-actin and smactin. There is a considerable variation in the immunoreactivity for these antigens in our case, as in the seven previously reported cases. These differences may be dependent on the degree of differentiation. The size of the tumour prompted us to recommend a careful clinical follow-up. The patient had an uneventful post-operative course, and there has been no evidence of relapses over 24 months of follow-up.