Three new pinolidoxins called epi-, dihydro-, and epoxy-pinolidoxin (2, 4, and 5, respectively)were isolated from Ascochyta pinodes grown on wheat, and theirs structures were determined using spectroscopic and chemical methods. They were characterized as 7-epi-, 5,6-dihydro-, and 5,6-epoxy-pinolidoxin, respectively. Assayed on pea and bean leaves, epipinolidoxin and dihydropinolidoxin caused necrotic lesions, whereas epoxypinolidoxin was inactive. Only epipinolidoxin and epoxypinolidoxin were active using the brine shrimp assay.
3 New Toxic Pinolidoxins From Ascochyta-pinodes / Evidente, Antonio; R., Capasso; M. A., Abouzeid; Lanzetta, Rosa; M., Vurro; A., Bottalico. - In: JOURNAL OF NATURAL PRODUCTS. - ISSN 0163-3864. - STAMPA. - 56:(1993), pp. 1937-1943. [10.1021/np50101a011]
3 New Toxic Pinolidoxins From Ascochyta-pinodes
EVIDENTE, ANTONIO;LANZETTA, ROSA;
1993
Abstract
Three new pinolidoxins called epi-, dihydro-, and epoxy-pinolidoxin (2, 4, and 5, respectively)were isolated from Ascochyta pinodes grown on wheat, and theirs structures were determined using spectroscopic and chemical methods. They were characterized as 7-epi-, 5,6-dihydro-, and 5,6-epoxy-pinolidoxin, respectively. Assayed on pea and bean leaves, epipinolidoxin and dihydropinolidoxin caused necrotic lesions, whereas epoxypinolidoxin was inactive. Only epipinolidoxin and epoxypinolidoxin were active using the brine shrimp assay.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
