Two new sesterterpenes, lintenolides F (6 a, b) and G (7 a, b), were isolated from the Caribbean sponge Cacospongia cf. linteiformis. Their stereostructures were determined using spectroscopic and chemical methods. The new compounds (6 a, b and 7 a, b) and the related compounds lintenolides A-E (1 a, b-5 a, b), previously isolated from the sponge, exhibited antiproliferative activity on four cell lines.
Antiproliferative sesterterpenes from the Caribbean sponge Cacospongia cf. linteiformis / Carotenuto, A.; Fattorusso, E.; Lanzotti, V.; Magno, S.; Carnuccio, Rosa; Iuvone, Teresa. - In: COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY. PART C, PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY. - ISSN 1367-8280. - STAMPA. - 119:(1998), pp. 119-123.
Antiproliferative sesterterpenes from the Caribbean sponge Cacospongia cf. linteiformis.
A. CarotenutoPrimo
;V. Lanzotti;CARNUCCIO, ROSA;IUVONE, TERESA
1998
Abstract
Two new sesterterpenes, lintenolides F (6 a, b) and G (7 a, b), were isolated from the Caribbean sponge Cacospongia cf. linteiformis. Their stereostructures were determined using spectroscopic and chemical methods. The new compounds (6 a, b and 7 a, b) and the related compounds lintenolides A-E (1 a, b-5 a, b), previously isolated from the sponge, exhibited antiproliferative activity on four cell lines.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
